UK Salengei Active Reveratrol

Maximum daily dose: 1 capsule
Polygonum cuspidatum extract (of which, 95% Trans-Resveratrol)	500 mg

Resveratrol is a phytoalexin. Stilbene in
grapes is formed in plants as a natural response when they are attacked
by fungi or bacteria, or ultraviolet radiation from the sun. It develops
in products such as wine, grape must, etc, and other foods such as
oysters, peanuts and walnuts, but one of the plants where it is found in
greater amounts is Polygonum cuspidatum (Japanese knotweed).
Resveratrol is also produced by chemical synthesis. This is important
when choosing, as the best resveratrol supplement is of natural origin
and comes from the Polygonum cuspidatum plant. Furthermore, its
bioavailability is increased, and has the active “Trans-resveratrol”
type.

Resveratrol is being used in numerous studies to see what its effects
in animals and humans are. In experiments with rats and mice,
beneficial effects such as anti-cancer, anti-inflammatory,
anti-fibrotic, reduced blood-sugar levels and cardiovascular benefits
have been reported.

Resveratrol induces expression of several genes such as FOXO1, FOXO3a
(related to longevity) and PBEF (involved in regulation of plasma
glucose levels). Other studies have also shown its role as sirtuin
activator (SirT1, Sirt3, SIRT4).

There are many studies on the beneficial effects of resveratrol,
independently of whether they are activators of sirtuins or not.

In one of the studies published in Nature, mice
that were subjected to a diet very rich in fats but were also
supplemented with high doses of resveratrol, did not suffer some of the
worst consequences of obesity, such as liver degeneration,
predisposition to diabetes and other symptoms of aging that often lead
to premature death, and their lifespan was extended compared to those
who did not receive the supplement.

In
another experiment, published in Cell, researchers noticed a significant
increase in energy expenditure in mice treated with resveratrol,
resulting in their protection against obesity and diabetes. With
this substance, the muscle fibres use more oxygen, both during
exercise, in which greater resistance is confirmed, as in periods of
inactivity. Delving
into the reason for these effects, scientists bumped into mitochondria –
which are responsible for energy production in muscles, and in whose
cells they are found in large quantities. They found that, indeed, proteins related to mitochondrial function are activated.

As for its role as an
ergogenic substance in sports, it has been shown in animal experiments
that it improves the physical capacity of animals subjected to a diet
enriched with this product. Human studies, however, are needed to clarify its true role in physiology and sports nutrition. Another
study suggests that resveratrol may be counterproductive in people
receiving chemotherapy with paclitaxel (a breast cancer management drug)
due to their metabolism, as it interacts with resveratrol.

Resveratrol shows promising results in preventing diabetes, colorectal cancer and Alzheimer’s. It is also being used in numerous studies to study its effects on animals and humans. In
order to be neutral and not seem commercially biased, if you want to
receive the abstracts of these and other publications we suggest that
you request them and we’ll be happy to provide them.